TOPMed Acknowledgements

TOPMed papers require acknowledgments for TOPMed sequencing as well as for study-specific data. Study-specific acknowledgments are specified on the Study-specific Acknowledgements webpage; general TOPMed acknowledgments are described below.

Please use the following template paragraph to acknowledge the use of TOPMed data in publications:

Whole genome sequencing (WGS) for the Trans-Omics in Precision Medicine (TOPMed) program was supported by the National Heart, Lung and Blood Institute (NHLBI).  WGS for "NHLBI TOPMed: <insert Study name (phs# with version extension)>" was performed at <insert sequencing center name (grant/contract number) from the Table below>. [Repeat this sentence for each TOPMed Study as appropriate.]  Centralized read mapping and genotype calling, along with variant quality metrics and filtering were provided by the TOPMed Informatics Research Center (3R01HL-117626-02S1).  Phenotype harmonization, data management, sample-identity QC, and general study coordination, were provided by the TOPMed Data Coordinating Center (3R01HL-120393-02S1). We gratefully acknowledge the studies and participants who provided biological samples and data for TOPMed. <Insert additional study-specific acknowledgments specified in the "Acknowledgment Statement" under "Study Attribution" on the "Study" tab of each accession's dbGaP home page>

For example, to acknowledge use of TOPMed data from the Framingham Heart Study and the Jackson Heart study (note that here we added a phs# extension “v1.p1” to denote the actual version that was downloaded and used; version numbers vary over time, so are not included in the table below):

Whole genome sequencing (WGS) for the Trans-Omics in Precision Medicine (TOPMed) program was supported by the National Heart, Lung and Blood Institute (NHLBI). WGS for “NHLBI TOPMed: Whole Genome Sequencing and Related Phenotypes in the Framingham Heart Study” (phs000974.v1.p1) was performed at the Broad Institute of MIT and Harvard (HHSN268201500014C).  WGS for “NHLBI TOPMed: The Jackson Heart Study” (phs000964.v1.p1) was performed at the University of Washington Northwest Genomics Center (HHSN268201100037C). Centralized read mapping and genotype calling, along with variant quality metrics and filtering were provided by the TOPMed Informatics Research Center (3R01HL-117626-02S1).  Phenotype harmonization, data management, sample-identity QC, and general study coordination, were provided by the TOPMed Data Coordinating Center (3R01HL-120393-02S1). We gratefully acknowledge the studies and participants who provided biological samples and data for TOPMed. <insert study-specific acknowledgments, which sometimes depend on what phenotypic and/or molecular data were used>

To easily find a phs number in the table below, use your browser's built in functionality to search this page (Ctrl-F or Cmd-F on most desktop computers).

Study Accession TOPMed Study Name Sequencing Center Sequencing Support
phs000993 NHLBI TOPMed: Heart and Vascular Health Study (HVH) BROAD, BAYLOR 3R01HL092577-06S1 (Phase 1:Broad, AFGen), 3U54HG003273-12S2 (Phase 2: Baylor, VTE, TOPMed supplement to NHGRI)
phs001062 NHLBI TOPMed: MGH Atrial Fibrillation Study BROAD 3R01HL092577-06S1
phs001024 NHLBI TOPMed: Partners HealthCare Biobank BROAD 3R01HL092577-06S1
phs001189 NHLBI TOPMed: Cleveland Clinic Atrial Fibrillation Study BROAD 3R01HL092577-06S1
phs000997 NHLBI TOPMed: The Vanderbilt AF Ablation Registry BROAD 3R01HL092577-06S1
phs001032 NHLBI TOPMed: The Vanderbilt Atrial Fibrillation Registry BROAD 3R01HL092577-06S1
phs001040 NHLBI TOPMed: Novel Risk Factors for the Development of Atrial Fibrillation in Women BROAD 3R01HL092577-06S1
phs000956 NHLBI TOPMed: Genetics of Cardiometabolic Health in the Amish BROAD 3R01HL121007-01S1
phs001143 NHLBI TOPMed: The Genetics and Epidemiology of Asthma in Barbados ILLUMINA 3R01HL104608-04S1
phs000954 NHLBI TOPMed: The Cleveland Family Study (WGS) UW NWGC 3R01HL098433-05S1
phs000951 NHLBI TOPMed: Genetic Epidemiology of COPD (COPDGene) in the TOPMed Program BROAD, UW NWGC HHSN268201500014C (Phase 2 Broad)
phs000946 NHLBI TOPMed: Boston Early-Onset COPD Study in the TOPMed Program UW NWGC 3R01HL089856-08S1
phs000988 NHLBI TOPMed: The Genetic Epidemiology of Asthma in Costa Rica UW NWGC 3R37HL066289-13S1
phs000974 NHLBI TOPMed: Whole Genome Sequencing and Related Phenotypes in the Framingham Heart Study BROAD 3R01HL092577-06S1 (AFGen)
phs000964 NHLBI TOPMed: The Jackson Heart Study UW NWGC HHSN268201100037C 
phs000920 NHLBI TOPMed: Genes-environments and Admixture in Latino Asthmatics (GALA II) Study NYGC 3R01HL117004-02S3
phs000921 NHLBI TOPMed: Study of African Americans, Asthma, Genes and Environment (SAGE) Study NYGC 3R01HL117004-02S3
phs000972 NHLBI TOPMed: Genome-wide Association Study of Adiposity in Samoans UW NWGC, NYGC HHSN268201100037C (Phase 1, UW NWGC), HHSN268201500016C (Phase 2, NYGC) 
phs001211 NHLBI TOPMed: Trans-Omics for Precision Medicine Whole Genome Sequencing Project: ARIC BAYLOR, BROAD 3R01HL092577-06S1 (Broad, AFGen), HHSN268201500015C (Baylor, VTE), 3U54HG003273-12S2 (Baylor, VTE)
phs001412 NHLBI TOPMed: Diabetes Heart Study African American Coronary Artery Calcification (AA CAC) BROAD HHSN268201500014C (Broad, AA_CAC)
phs001345 NHLBI TOPMed: Genetic Epidemiology Network of Arteriopathy (GENOA) BROAD, UW NWGC HHSN268201500014C (Broad, AA_CAC), 3R01HL055673-18S1 (UW NWGC, HyperGEN_GENOA)
phs001218 NHLBI TOPMed: GeneSTAR (Genetic Study of Atherosclerosis Risk) MACROGEN, BROAD HHSN268201500014C (Broad, AA_CAC)
phs001217 NHLBI TOPMed: Genetic Epidemiology Network of Salt Sensitivity (GenSalt) BAYLOR HHSN268201500015C
phs001359 NHLBI TOPMed: Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) UW NWGC 3R01HL104135-04S1
phs001293 NHLBI TOPMed: HyperGEN - Genetics of Left Ventricular (LV) Hypertrophy UW NWGC 3R01HL055673-18S1
phs001416
NHLBI TOPMed: MESA and MESA Family AA-CAC BROAD 3U54HG003067-13S1 (MESA, TOPMed supplement to NHGRI), HHSN268201500014C (Broad, AA_CAC)
phs001215 NHLBI TOPMed: San Antonio Family Heart Study (WGS) ILLUMINA 3R01HL113323-03S1
phs001207 NHLBI TOPMed: African American Sarcoidosis Genetics Resource BAYLOR 3R01HL113326-04S1
phs001387 NHLBI TOPMed: Rare Variants for Hypertension in Taiwan Chinese (THRV) BAYLOR 3R01HL111249-04S1, HHSN26820150015C
phs001368 NHLBI TOPMed: Cardiovascular Health Study BAYLOR HHSN268201500015C (VTE portion of CHS)
phs001402 NHLBI TOPMed: Whole Genome Sequencing of Venous Thromboembolism (WGS of VTE) BAYLOR HHSN268201500015C, 3U54HG003273-12S2 
phs001237 NHLBI TOPMed: Women's Health Initiative (WHI) BROAD HHSN268201500014C
NYGC = New York Genome Center; BROAD = Broad Institute of MIT and Harvard; UW NWGC = University of Washington Northwest Genomics Center; ILLUMINA = Illumina Genomic Services; MACROGEN = Macrogen Corp.; BAYLOR = Baylor Human Genome Sequencing Center