Data Coordinating Center (DCC)

The Data Coordinating Center is based in the Biostatistics Department at the University of Washington and is led by Ken Rice (contact PI), Bruce Weir (co-PI), Bruce Psaty (co-PI), and Cathy Laurie. The group is advised by Eric Boerwinkle (Baylor College of Medicine, Human Genome Sequencing Center), Stephen Rich (University of Virginia) and Adrienne Cupples (Boston University).  Michael Bowers, David Beame and Kate Wehr are our contacts for administrative and logistical issues. Quenna Wong is our main contact for dbGaP registration, sample tracking and phenotype harmonization. Our analytic and support staff are based in the Biostatistics Department and the Cardiovascular Health Research Unit. To reach the DCC administrators, please email gccbiost@uw.edu.

The DCC has the following main aims:

  1. Provide administrative and logistical support to this study. To facilitate interactions and learning, we will maintain web-based collaboration tools, and will organize symposia and workshops.
  2. Establish phenotype-focused working groups, identify opportunities for cross-study analyses and harmonize phenotypic data accordingly.
  3. Coordinate activities across the sequencing centers and studies, including design and implementation of technical controls, tracking sequencing progress and facilitating study registrations for dbGaP.
  4. Develop guidelines and methodology for rare variant analyses and perform analyses to assess the utility of various approaches.