Diabetes Heart Study

Institution(s): 
Wake Forest Baptist Health

Project:

PI: 
Nicholette Palmer
NIH Program Officer: 
Starting Phase: 
Phase 2
Phases Involved: 
2
Co-PI: 
Donald W. Bowden
Phenotype Liaison: 
Short Name: 
DHS
Omics Center(s) Phase 2: 
Broad Institute Genomics Platform
Type of Omics: 
WGS
External Funding: 
TOPMed Accession #: 
Description: 

African American Diabetes Heart Study (AA-DHS) objectives are to improve understanding of ethnic differences in coronary artery calcification (CAC) and carotid plaque (CP) in populations of African and European ancestry. The AA-DHS consists of self-reported African Americans with T2D recruited from two Wake Forest School of Medicine (WFSM) studies: the family-based Diabetes Heart Study (DHS) and unrelated individuals in the AA-DHS. DHS is a cross-sectional study of European American and African American families with siblings concordant for T2D. AA-DHS started after DHS and enrolled unrelated African Americans. Written informed consent was obtained from all participants and all study protocols were approved by the WFSM institutional review board.