Award Type: U01 NHLBI TOPMed Program: Integrative Omics Approaches for Analysis of TOPMed Data
Title Investigator(s) Award number
U01: Rice and Weir - From gene regions to whole chromosomes: scaling up association-finding for disease and omics outcomes in TOPMed Ken Rice, Bruce Weir U01 HL137162-01
U01: O'Connell - High-performance mixed model toolset for integrative omics analysis of big data Jeff O'Connell U01 HL137181-01
U01: Kang - Scalable and translational analysis tools on the cloud for deep integrative omics data Hyun Min Kang U01 HL137182-01
U01: Haussler and Paten - Unbiased analysis of genomic correlates of gene expression in health and disease David Haussler, Benedict Paten U01 HL137183-01
U01: Benos and Sciurba - Systems level causal discovery in heterogeneous TOPMed data Takis Benos, Frank Sciurba U01 HL137159-01
Award Type: R01 Integrative Computational Biology for Analysis of NHLBI TOPMed Data
Title Investigator(s) Award number
R01: Yu - Trans-omics Analysis to Unravel Molecular Underpinnings of Heart, Lung and Blood Disease Risk Factors Bing Yu R01 HL142003-01
R01: Montgomery - Integrative multi-omics in whole genome studies of HLBS disorders Stephen Montgomery R01 HL142015-01
R01: Mathias - Integrative computational biology approaches to identify functional determinants of platelet aggregation in African Americans and European Americans Rasika Mathias R01 HL141944-01
R01: Lee - Integrative analysis to uncover biology of blood lipids & coronary heart disease Seunggeun Shawn Lee, Cristen Willer, Xiang Zhou R01 HL142023-01
R01: Lappalainen - Integration of omics data to improve interpretation of genetic risk variants in lung disease Tuuli Lappalainen, R. Graham Barr R01 HL142028-01
R01: Himes - Integrative Analyses to Uncover Biological Mechanisms Mediating Gene Associations with Asthma Drug Response Among Minority Children Blanca Himes R01 HL141992-01
R01: Chakravarti - Cardiac genetic effects across HLBS phenotypes Aravinda Chakravarti R01 HL141980-01
Award Type: Working Group Analysis Support Program
Title Investigator(s) Analysis Center Working Group or Committee
ASP: Seyerle and Coombes - WGS of venous thromboembolism Amanda Seyerle, Brandon Coombes DCC Venous Thromboembolism
ASP: Natarajan and Peloso - Whole genome allelic determinants of severe dyslipidemia Pradeep Natarajan, Gina Peloso Broad Lipids
ASP: Manichaikul and Cho - Pulmonary function and COPD Ani Manichaikul, Michael Cho IRC Chronic Obstructive Pulmonary Disease, PFT Lung Population Cohorts
ASP: Kelly - WGS of blood pressure Tanika Kelly Baylor Blood Pressure
ASP: Fetterman - Relations of mitochondrial genetic variation with cardiometabolic disease Jessica Fetterman IRC Mitochondrial DNA
ASP: Choi - WGS for atrial fibrillation and EKG traits Seung Hoan Choi Broad EKG - Arrhythmia
ASP: Chen and Huffman - Computational pipeline for whole-genome analysis of complex traits Han Chen, Jennifer Huffman DCC Analysis